We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.
Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.
This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.
However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
Most Useful Reviews
9
Reduced migraine symptoms
18 people found this helpful
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
Read More
7.5
Improved energy levels
10 people found this helpful
I'm pleased to find this in capsule form by Solgar, which is known for quality. Since taking these vitamins, my constant fatigue has disappeared, my sleep has improved, and my hair no longer falls out. I feel my heart is healthier, and skin irritations have vanished. These vitamins are essential for my body during stressful times.
Read More
7.5
Enhanced mood stability
3 people found this helpful
After starting this complex, my joint pain and depressive feelings have lessened. I noticed changes within a week, feeling more energetic and stable emotionally. This Solgar vitamin B supports my cardiovascular health and nervous system, and I appreciate its mild taste and high quality.
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.
Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.
This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.
However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Niacin intake lowers mortality risks
Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018.
We looked into how dietary niacin might affect mortality rates, particularly for cardiovascular disease. Analyzing data from nearly 27,000 U.S. adults over about nine years, we found that those with the highest niacin intake had a significantly lower risk of dying from any cause, as well as from heart-related issues.
Interestingly, this protective effect was more robust among those without diabetes, suggesting that niacin's benefits can vary by health condition. Our findings highlight the potential role of diet in supporting heart health.
Read More
7
Vitamin B influence on hypertension
Relationship between blood pressure variability and vitamin B level in essential hypertension.
We investigated the connection between blood pressure variability (BPV) and vitamin B6 and B12 levels in individuals with essential hypertension. Our study involved 100 patients with hypertension and a control group of 100 healthy individuals.
We found that patients with hypertension had significantly lower levels of these B vitamins compared to the healthy group. Additionally, those with higher B vitamin levels exhibited reduced BPV.
This suggests that Vitamin B6 and B12 may influence blood pressure control, providing insights into hypertension management strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Reduced migraine symptoms
18 people found this helpful
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
Read More
7.5
Improved energy levels
10 people found this helpful
I'm pleased to find this in capsule form by Solgar, which is known for quality. Since taking these vitamins, my constant fatigue has disappeared, my sleep has improved, and my hair no longer falls out. I feel my heart is healthier, and skin irritations have vanished. These vitamins are essential for my body during stressful times.
Read More
7.5
Enhanced mood stability
3 people found this helpful
After starting this complex, my joint pain and depressive feelings have lessened. I noticed changes within a week, feeling more energetic and stable emotionally. This Solgar vitamin B supports my cardiovascular health and nervous system, and I appreciate its mild taste and high quality.
Read More
8
Effective stress relief
1 people found this helpful
This is a high-quality complex supporting cardiovascular health and energy. It effectively relieves irritability and stress. One capsule with meals suffices, and despite their water-soluble nature, I notice improved appetite and skin condition without any adverse effects on my body.
Read More
7.5
Boosted immune system
1 people found this helpful
B vitamins are vital for energy, emotional health, and multiple bodily functions including combatting cardiovascular disease. Insufficient B vitamins can lead to fatigue and poor memory. The synergy of this complex is effective for enhancing overall health.
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
Based on user reviews, many individuals report noticing positive changes in their cardiovascular health within a week of starting a B-Complex supplement. For instance, one user highlighted feeling more energetic and emotionally stable just seven days after beginning the regimen, which they credited to the support of their cardiovascular health (Read Review). Others have expressed improvements in overall well-being, including reduced stress and healthier cardiovascular function, although specific timelines for these benefits can vary.
Additionally, several users suggest that consistent use of the supplement may lead to increasingly noticeable results, contributing to long-term health improvements. For example, another review noted a comprehensive enhancement in health metrics over time, particularly with regards to energy and stress management (Read Review). However, individual experiences can differ, and some users may take longer to observe significant effects on cardiovascular conditions. Therefore, if you're considering this supplement for cardiovascular disease, expect to evaluate your response within the first few weeks.
When considering supplements for cardiovascular disease prevention and management, specific B vitamins appear to hold promise based on recent scientific studies. For instance, vitamin B6 has demonstrated a significant role in heart recovery post-heart attacks by promoting angiogenesis, thereby improving heart function and reducing inflammation in experimental models [2]. Furthermore, patients with hypertension were found to have lower levels of vitamins B6 and B12 compared to healthy controls, indicating that supplementation might help regulate blood pressure for some individuals [1].
Additionally, another study linked higher levels of folate with a slower increase in carotid intima-media thickness, an important marker for heart disease, suggesting a protective effect against cardiovascular complications [4]. Overall, while evidence points towards the potential benefits of specific B vitamins, including folate and niacin, as contributory factors to cardiovascular health, it's essential to consult a healthcare provider before starting any supplementation regime, especially to understand how it might interact with existing health conditions.
Based on user reviews, there are several notable improvements reported by individuals taking B-Complex supplements. Users have expressed significant reductions in migraine frequency and intensity, with one reviewer mentioning that their migraine attacks decreased from seven times a month to just one, along with a reduction in the need for triptan medications (Read Review). Others have experienced a remarkable boost in energy levels, better sleep quality, and emotional stability, indicating an overall enhancement in well-being after just a week of use (Read Review).
Several users also report improvements related to cardiovascular health, increased stress resistance, and alleviation of symptoms like irritability and fatigue. For example, one user noted a feeling of restored mental and physical well-being since incorporating the vitamins into their routine (Read Review). However, individual results can vary significantly, and some may take longer to experience these benefits. Therefore, it’s essential to monitor your own response to the supplement over time to fully gauge its effect on your health.
Based on user reviews, many individuals report significant benefits when combining B-Complex supplements with other nutritional aids for cardiovascular health. For instance, one user noted that the B vitamins helped them cope with fatigue and enhance their emotional stability, attributing these improvements to the support of cardiovascular health in tandem with dietary changes (Read Review). Furthermore, users have emphasized the synergy between B-Complex and omega fatty acids, stating that omega-3s are invaluable for cardiovascular health, potentially lowering the risk of coronary heart disease when paired with B vitamins (Read Review).
Additionally, some reviewers have shared their experiences of stress resistance and overall health improvements when combining B-Complex with other strategies aimed at cardiovascular wellness. For example, one individual reported that their cardiovascular health felt notably supported with consistent intake of these vitamins, indicating that the combination likely yields positive effects on stress and overall well-being (Read Review). While user experiences vary, many agree on the supplements' collective potential to enhance heart health, energy levels, and emotional balance.
Based on user reviews, there seems to be a consensus that doses of Vitamin B Complex are typically effective when taken in moderation. Many users report positive changes in their cardiovascular health, energy levels, and overall well-being while consuming just one capsule per day with meals, highlighting its potency and absorption. For instance, one reviewer stated, "One capsule with meals suffices," indicating that this dose was adequate for supporting cardiovascular health and alleviating stress without causing adverse effects Read Review.
Moreover, users have noted that the B vitamins are essential in promoting heart health and managing stress, with one reviewer emphasizing the importance of B vitamins for overall vitality. They commented, "Insufficient B vitamins can lead to fatigue and poor memory," suggesting that maintaining an appropriate dosage is crucial for maximizing the benefits related to cardiovascular disease Read Review. While specific dosage recommendations were not explicitly mentioned in the reviews, it is clear that users experienced significant improvements in health variables while adhering to a simple regimen.
7.5
Enhanced mood stability
3 people found this helpful
After starting this complex, my joint pain and depressive feelings have lessened. I noticed changes within a week, feeling more energetic and stable emotionally. This Solgar vitamin B supports my cardiovascular health and nervous system, and I appreciate its mild taste and high quality.
9
Essential vitamin support
Founded in 1947, this B-Complex supports energy metabolism and helps manage the stresses of daily life. The individual B vitamins’re critical for maintaining healthy metabolism, particularly addressing cardiovascular disease.
9
Reduced migraine symptoms
18 people found this helpful
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
7.5
Boosts energy levels
B complex vitamins support the conversion of carbohydrates, proteins, and fats into energy. They help alleviate fatigue, stress, anxiety, and depression, while promoting the long-term health of the cardiovascular system, nervous system, immune function, skin, hair, liver, and muscles. I have felt restored mentally and physically since I started taking them.
7.5
Supports cardiovascular health
Omega 369 is essential for cardiovascular health, formulated with beneficial oils. Research indicates omega-3s might lower coronary heart disease risk, making this a valuable addition to my daily regimen.
9
Improved resilience
Excellent! I’ve witnessed an increase in stress resistance and overall support for my cardiovascular and nervous system.
8
Effective stress relief
1 people found this helpful
This is a high-quality complex supporting cardiovascular health and energy. It effectively relieves irritability and stress. One capsule with meals suffices, and despite their water-soluble nature, I notice improved appetite and skin condition without any adverse effects on my body.
7.5
Boosted immune system
1 people found this helpful
B vitamins are vital for energy, emotional health, and multiple bodily functions including combatting cardiovascular disease. Insufficient B vitamins can lead to fatigue and poor memory. The synergy of this complex is effective for enhancing overall health.
9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
7
Vitamin B influence on hypertension
Relationship between blood pressure variability and vitamin B level in essential hypertension.
We investigated the connection between blood pressure variability (BPV) and vitamin B6 and B12 levels in individuals with essential hypertension. Our study involved 100 patients with hypertension and a control group of 100 healthy individuals.
We found that patients with hypertension had significantly lower levels of these B vitamins compared to the healthy group. Additionally, those with higher B vitamin levels exhibited reduced BPV.
This suggests that Vitamin B6 and B12 may influence blood pressure control, providing insights into hypertension management strategies.
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
References
Bian XY, Cui C, Zhang QY. Relationship between blood pressure variability and vitamin B level in essential hypertension. J Physiol Pharmacol. 2025;76. doi:10.26402/jpp.2025.1.02
Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413
Song Y, Choi JE, Park JM, Kwon YJ, Hong KW, et al. Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES). Nutrients. 2024;16. doi:10.3390/nu16234147
Palchetti CZ, Gonçalves NG, Suemoto CK, Santos IS, Lotufo PA, et al. Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification. Clin Nutr ESPEN. 2025;65:144. doi:10.1016/j.clnesp.2024.11.034
Lin L, Chen S, Zhang C, Li L, Chen Y, et al. Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018. Sci Rep. 2024;14:28313. doi:10.1038/s41598-024-79986-9